The purpose of the study is to evaluate the policy commitment of North Sumatera provincial government in mitigating climate change (case study of mangrove protection).The Regional Action Plan for Greenhouse Gas (RAD-GRK) has been adopted in 2012 by the Province of North Sumatra.The action plan identifies action needed to rehabilitate mangroveswithi

Embedded Convolutional Neural Networks (ConvNets) are driving the evolution of ubiquitous systems that can sense and understand the environment autonomously.Due to their high complexity, aggressive compression is needed to meet the specifications of portable end-nodes.A variety of algorithmic optimizations are available today, from custom quantizat

To give full play to the advantages of pure electric drive, and aimed at the transmission system of electric loader, the low efficiency hydraulic torque converter and reverse direction clutch of traditional models are cancelled.By analyzing the shift law of the pure electric drive system, the electro-hydraulic shift control system is used to contro

The European Medical Agency (EMA) has issued a draft guideline on the quality and equivalence of topical products.The equivalence for complex semisolid formulations involves several steps: the same quantitative content, the same microstructure, the same release, and permeation profile.In this paper, several batches of a low strength topical product

Summary: BRCA1 promotes homologous recombination (HR) by activating DNA-end resection.By contrast, 53BP1 forms a barrier that inhibits DNA-end resection.Here, we show that BRCA1 promotes DNA-end resection by relieving the 53BP1-dependent barrier.We show that 53BP1 is phosphorylated by ATM in S/G2 phase, promoting RIF1 recruitment, which inhibits re